{"search_session":{},"preferences":{"l":"fr","queryLanguage":"fr"},"patentId":"030-320-528-921-82X","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"030-320-528-921-82X","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11848,"type":"PATENT","title":"University of Leipzig Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11627,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8460,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
R1, R2 which may be identical or different denote hydrogen or a group selected from among C1-C6-alkyl, C2-C6-alkenyl and C2-C6-alkynyl, wherein each group may be optionally substituted by fluorine,\n
or\n
R1 and R2 together denote a 2- to 5-membered alkyl bridge,\n
R3 denotes hydrogen or a group selected from among C1-C12-alkyl optionally substituted by fluorine, C2-C12-alkenyl optionally substituted by fluorine, C2-C12-alkynyl optionally substituted by fluorine and C6-C14-aryl optionally substituted by one or more groups selected from OH, NO2, CN, OMe, —OCHF2, —OCF3, —NH2, halogen and C1-C10-alkyl, or a group selected from among C3-C12-cycloalkyl optionally substituted by one or more groups selected from OH, NO2, CN, OMe, —OCHF2, —OCF3, —NH2, halogen, C1-C10-alkyl, —O—C1-C3-alkyl, —COOH, —COO—C1-C4-alkyl and —CONH2, C3-C12-cycloalkenyl, C7-C12-polycycloalkyl, C7-C12-polycycloalkenyl and C5-C12-spirocycloalkyl,\n
R4 denotes a group selected from among hydrogen, hydroxy and halogen, or a group selected from among C1-C3-alkyl optionally substituted by fluorine, C2-C6-alkenyl optionally substituted by fluorine, C2-C6-alkynyl optionally substituted by fluorine, C1-C5-alkyloxy, C2-C5-alkenyloxy and C2-C5-alkynyloxy,\n
L denotes a linker selected from among C2-C10-alkyl optionally substituted by fluorine, C2-C10-alkenyl optionally substituted by fluorine, C6-C14-aryl optionally substituted by one or more groups selected from OH, NO2, CN, OMe, —OCHF2, —OCF3, —NH2, halogen and C1-C10-alkyl, -C1-C4-alkyl-C6-C14-aryl, C6-C14-heteroaryl wherein up to two C atoms are replaced by one or two nitrogen atoms, while these heteroaryl rings may optionally be anellated to a benzene ring and may optionally carry one or more substituents selected from F, Cl, Br, OH, OMe, methyl, ethyl, CN, CONH2, NH2, phenyl, pyridyl, and C3-C12-cycloalkyl optionally substituted by one or more groups selected from OH, NO2, CN, OMe, —OCHF2, —OCF3, —NH2, halogen, C1-C10-alkyl, —O—C1-C3-alkyl, —COOH, —COO—C1-C4-alkyl and —CONH2,\n
n denotes 0 or 1,\n
R5 denotes a group selected from among hydrogen or C1-C6-alkyl optionally substituted by fluorine, C1-C6-alkenyl optionally substituted by fluorine, C1-C6-alkynyl optionally substituted by fluorine, C3-C12-cycloalkyl optionally substituted by one or more groups selected from OH, NO2, CN, OMe, —OCHF2, —OCF3, —NH2, halogen, C1-C10-alkyl, —O—C1-C3-alkyl, —COOH, —COO—C1-C4-alkyl and —CONH2, or a group selected from among pyridyl, morpholinyl, piperidinyl, piperazinyl, piperazinylcarbonyl, pyrrolidinyl, tropenyl, sulphoxomorpholinyl, sulphonylmorpholinyl, thiomorpholinyl and azacycloheptyl, optionally in the form of the tautomer, the racemate, the enantiomer, the diastereomer or the mixture thereof, or optionally a pharmacologically acceptable acid addition salt thereof."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 1, wherein\n
R3 to R5, n and L are as hereinbefore defined, and\n
R1, R2 which may be identical or different denote hydrogen , or a group selected from among methyl, ethyl, propyl, propargyl and allyl,\n
or\n
R1 and R2 together represent cyclopropyl."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 2, wherein\n
R5 denotes a group selected from among hydrogen or C1-C6-alkyl optionally substituted by fluorine, C3-C12-cycloalkyl optionally substituted by one or more groups selected from OH, NO2, CN, OMe, —OCHF2, —OCF3, —NH2, halogen, C1-C10-alkyl, —O—C1-C3-alkyl, —COOH, —COO—C1-C4-alkyl and —CONH2,\n
or a group selected from among pyridyl, morpholinyl, piperidinyl, piperazinyl and piperazinylcarbonyl."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The method according claim 3, wherein\n
R3 denotes hydrogen, C1-C6-alkyl optionally substituted by fluorine, or C3-C12-cycloalkyl optionally substituted by one or more groups selected from OH, NO2, CN, OMe, —OCHF2, —OCF3, —NH2, halogen, C1-C10-alkyl, —O—C1-C3-alkyl, —COOH, —COO—C1-C4-alkyl and —CONH2."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The method according claim 4, wherein\n
R4 denotes a group selected from among hydrogen, hydroxy, halogen, methyl, ethyl, propynyloxy and methoxy."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 1 wherein the compound is chosen from compounds of formula (I) listed in Table\n(I)\n ConfigR1/R2R1R2R3R4Ln-R5racH\n\nH\n racH\n\nH\n racH\n\nH\n racH\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\nH racH\n\n\n\n racH\n\n\n\n racH\n\nH\n racH\n\nH\n racH\n\nH\n racH\n\nH\n racH\n\nH\n racH\n\nH\n HH\nH\n \n\n\nH\n \n\n\nH\n \n\n\nHH \n\n\nH\n \n\n\nH\n \n\n\nH\n \n\n\n\n\n \n\n\n\n\n \n\n\n\n\n \n\n\n\nH \n\n\n\n\n racH\n\nH\n racH\n\nH\n racH\n\nH\n racH\n\nH\n racH\n\nHH racH\n\nH\n racH\n\nH\n \n\n\n\n\n \n\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\n\n racH\n\n\nH racH\n\nH\n racH\n\n\n\n RH\n\n\n\n RH\n\n\n\n RH\n\n\n\n RH\n\n\n\n RH\n\n\n\n RH\n\n\nH RH\n\n\n\n RH\n\n\n\n\noptionally in the form of the tautomer, the racemate, the enantiomer, the diastereomer or the mixture thereof, or optionally a pharmacologically acceptable acid addition salt thereof."],"number":6,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}