Inhibitors Of Ncca-atp Channels For Therapy

Abstract

Methods and compositions are provided that are utilized for treatment and/or prevention of intraventricular hemorrhage or progressive hemorrhagic necrosis (PHN), particularly following spinal cord injury. In particular, the methods and compositions are inhibitors of a particular NCca-ATP channel and include, for example, inhibitors of SUR1 and/or inhibitors of TRPM4. Kits for treatment and/or prevention of intraventricular hemorrhage or progressive hemorrhagic necrosis (PHN), particularly following spinal cord injury, are also provided. The present invention also concerns treatment and/or prevention of intraventricular hemorrhage in infants, including premature infants utilizing one or more inhibitors of the channel is provided to the infant, for example to brain cells of the infant.


Claims
Download PDF
Document Preview
Document History
  • Publication: Oct 15, 2013
  • Application: Jun 20, 2008
    US US 66585308 A
  • Priority: Jun 20, 2008
    US US 66585308 A
  • Priority: Jun 20, 2008
    US US 2008/0067640 W
  • Priority: Jun 22, 2007
    US US 94563607 P
  • Priority: Jun 22, 2007
    US US 94581107 P
  • Priority: Jun 22, 2007
    US US 94582507 P

Download Citation


Sign in to the Lens

Feedback