Abstract
The present disclosure relates to a composition for preventing or treating metabolic diseases, in which the composition includes Bacteroides acidifaciens as an active ingredient. In addition, the present disclosure relates to a composition for oxidizing fat or inhibiting DPP-4, in which the composition includes Bacteroides acidifaciens as an active ingredient. In addition, the present disclosure relates to a transformant expressing a lean phenotype, in which an Atg7 gene is deleted in dendritic cells.
Claims
- A method for treating obesity in a subject, the method comprising administering a pharmaceutically-effective amount of Bacteroides acidifaciens to the subject in need of treatment of obesity.
- A method for treating obesity according to claim 1, wherein the Bacteroides acidifaciens activates fat oxidation in adipose tissue.
- A method for treating obesity according to claim 1, wherein the subject administered the pharmaceutically-effective amount of Bacteroides acidifaciens has a higher amount of intestinal total bacteria as compared to an obese person not administered the pharmaceutically-effective amount of Bacteroides acidifaciens.
Owners (US)
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Gi Biome
(Apr 05 2019)
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The Asan Foundation
(Jul 26 2017)
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Applicants
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The Asan Found
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Gi Biome
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Inventors
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Kweon Mi Na
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Yang Jin Young
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CPC Classifications
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A61K35/74
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A23L33/135
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A23L33/30
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A23L33/40
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A23V2002/00
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A61K35/66
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A61K38/1709
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A61K45/06
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C12N5/0639
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C12N2510/00
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IPC Classifications
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A23L33/00
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A23L33/135
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A61K35/66
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A61K35/74
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A61K38/17
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A61K45/06
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C12N5/0784
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Document Preview
- Publication: Aug 6, 2019
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Application:
Dec 8, 2015
US 201515534068 A
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Priority:
Dec 8, 2015
KR 2015013402 W
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Priority:
Dec 8, 2014
KR 20140175349 A