Method For Identifying Agents Capable Of Inhibiting Apobec3c Activity In Hiv-infected Cells

Abstract

The present invention provides methods of identifying agents that reduce a level of active APOBEC3C in a cell. The present invention provides agents that reduce a level of active APOBEC3C in a cell; and compositions comprising the agents. The present invention further provides methods of reducing the mutation rate of a lentivirus in a cell; and methods of reducing the emergence of drug-resistant strains of lentivirus. The present invention further provides methods for treating lentivirus infections.


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Document History
  • Publication: Mar 13, 2012
  • Application: Oct 31, 2005
    US US 57707705 A
  • Priority: Oct 31, 2005
    US US 57707705 A
  • Priority: Oct 31, 2005
    US US 2005/0039522 W
  • Priority: Nov 2, 2004
    US US 62466404 P

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