Systems And Methods For Identifying Sequence Variation


Abstract Systems and method for determining variants can receive mapped reads, and call variants. In embodiments, flow space information for the reads can be aligned to a flow space representation of a corresponding portion of the reference. Reads spanning a position with a potential variant can be grouped and a score can be calculated for the variant. Based on the scores, a list of probable variants can be provided. In various embodiments, low frequency variants can be identified where multiple potential variants are present at a position.

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Document History
  • Publication: Mar 28, 2013
  • Application: Sep 20, 2012
    WO US 2012/0056397 W
  • Priority: May 9, 2012
    US US 201261644771 P
  • Priority: Jan 9, 2012
    US US 201261584391 P
  • Priority: Oct 10, 2011
    US US 201161545450 P
  • Priority: Sep 20, 2011
    US US 201161536967 P

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