Use Of Ketogenic Compounds For Treatment Of Age-associated Memory Impairment

Abstract

This invention relates to the field of therapeutic agents for the treatment of Age-Associated Memory Impairment (AAMI). In particular, the present invention utilizes compositions comprising at least one compound capable of elevating ketone body concentrations in a mammal (e.g., ketogenic compounds), administered in an amount effective for treatment or prevention of loss of cognitive function caused by reduced neuronal metabolism in AAMI. In one embodiment, the composition includes medium chain triglycerides (MCT). In another embodiment, the compositions are administered in the presence of carbohydrate. The present invention also relates to oral dosage forms, in particular, a nutritional drink comprising at least one compound capable of elevating ketone body concentrations in a mammal.


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Document History
  • Publication: Jun 10, 2014
  • Application: Jan 25, 2012
    US US 201213358257 A
  • Priority: Jan 25, 2012
    US US 201213358257 A
  • Priority: Apr 24, 2008
    US US 6485008 A
  • Priority: Apr 3, 2007
    US US 2007/0065873 W
  • Priority: Apr 3, 2006
    US US 74414006 P

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