Dna Expression Vectors And Methods Of Use


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The present invention provides novel pGA constructs which are useful as vectors for the delivery of DNA vaccine inserts. The vaccine inserts can include the DNA transcripts of various virus, bacteria, parasite and/or fungi. Also described are methods of raising multi-epitope CD8 T-cell responses by administering therapeutically effective amounts of the novel pGA constructs comprising pathogen vaccine inserts followed by booster immunizations with a live vectored vaccine comprising the same vaccine inserts.


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Document History
  • Publication: Nov 23, 2011
  • Application: Mar 2, 2001
    EP EP 10184748 A
  • Priority: Mar 2, 2001
    EP EP 01981921 A
  • Priority: Dec 1, 2000
    US US 25108300 P
  • Priority: Mar 2, 2000
    US US 18636400 P

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