Abstract
The invention provides antibodies that specifically bind transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, among other applications.
Claims
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Applicants
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Prothena Biosciences Ltd
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Univ Health Network
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Inventors
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Liu Yue
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Nijjar Tarlochan S
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Chakrabartty Avijit
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Higaki Jeffrey N
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CPC Classifications
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C07K16/18
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A61K2039/505
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C07K2317/24
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C07K2317/34
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C07K2317/56
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C07K2317/565
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C07K2317/567
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C07K2317/76
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C07K2317/92
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Document History
- Publication: Feb 15, 2018
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Application:
Jun 30, 2017
IB 2017053984 W
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Priority:
Jul 2, 2016
US 201615201423 A