Batches Of Recombinant Adenovirus With Altered Terminal Ends


The invention provides a composition comprising a plurality of recombinant adenovirus particles, being a recombinant human adenovirus of serotype 5, 26, 34, 35, 48,49 or 50, or a recombinant simian adenovirus, characterized in that the genomes of essentially all adenovirus particles in said composition comprise as the 5' terminal nucleotides the nucleotide sequence: CTATCTAT. The invention also provides methods to produce such compositions.

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Document History
  • Publication: Sep 19, 2013
  • Application: Mar 11, 2013
    WO EP 2013054846 W
  • Priority: Mar 12, 2012
    US US 201261609678 P
  • Priority: Mar 12, 2012
    EP EP 12159009 A

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