Compositions And Methods For Efficent Amplification Of Retinal Progenitors Cells

Abstract

The invention pertains to a defined cell culture medium for the expansion of human retinal progenitors, comprising or consisting of a nutrient medium, a SHH-pathway activator and a GSK3 inhibitor. To the use of said defined cell culture medium for the expansion of retinal progenitors, as well as to an in vitro method for expanding retinal progenitors, comprising :(i) placing a culture of human retinal progenitors in a defined cell culture medium as defined in claims 1 to 8; and (ii) culturing the cells in said defined cell culture medium.


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Document History
  • Publication: Sep 12, 2019
  • Application: Mar 6, 2019
    WO EP 2019055599 W
  • Priority: Mar 7, 2018
    EP EP 18305243 A

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