Anti-transthyretin Humanized Antibody

  • Published: Jun 28, 2017
  • Earliest Priority: Jan 29 2014
  • Family: 7
  • Cited Works: 9
  • Cited by: 0
  • Cites: 5
  • Additional Info: Cited Works
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Abstract

A humanized antibody which comprises a complementarity determining region of an H chain consisting of the amino acid sequence as shown in SEQ ID NOs: 1 to 3 and a complementarity determining region of an L chain consisting of the amino acid sequence as shown in SEQ ID NOs: 4 to 6. The humanized antibody of the present invention has the activity to specifically bind to transthyretin (TTR) with structural change and the activity to inhibit fibrillization of TTR and is a humanized antibody suitable for application to human body.


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Document History
  • Publication: Jun 28, 2017
  • Application: Jan 23, 2015
    EP EP 15743230 A
  • Priority: Jan 23, 2015
    JP 2015051856 W
  • Priority: Jan 29, 2014
    JP 2014014911 A

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