Il-17 Homologous Polypeptides And Therapeutic Uses Thereof

Abstract

The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and hosT-cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.


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Document History
  • Publication: Feb 5, 2009
  • Application: Jun 19, 2008
    US US 21476208 A
  • Priority: Jun 19, 2008
    US US 21476208 A
  • Priority: Jun 10, 2003
    US US 45857303 A
  • Priority: Jun 5, 2001
    US US 87450301 A
  • Priority: Mar 22, 2001
    US US 81674401 A
  • Priority: Feb 28, 2001
    US US 0106520 W
  • Priority: Dec 20, 2000
    US US 74725900 A
  • Priority: Aug 24, 2000
    US US 0023328 W
  • Priority: Mar 21, 2000
    US US 19100700 P

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