Inhibitors Of Proteasomal Activity For Stimulating Bone Growth


The present invention relates to compounds that inhibit the activity of the proteasome or the productions of proteasomal proteins and promote bone formation and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgey, and post-dental implantation, in subject where this is desirable.

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Document History
  • Publication: Jan 4, 2005
  • Application: Oct 23, 2000
    US US 69580700 A
  • Priority: Oct 23, 2000
    US US 69580700 A
  • Priority: Oct 20, 1999
    US US 42154599 A
  • Priority: Jul 27, 1999
    US US 36177599 A
  • Priority: Jul 10, 1998
    US US 11394798 A

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