Dna Methylation Markers For Metastatic Prostate Cancer

Abstract

The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for assessing prostate cancer. In a specific embodiment, present inventors have developed and applied a new technology and associated computation methods enabling simultaneous genome-scale analysis of genetic (copy number) and epigenetic (total methylation (TM) and allele-specific methylation (ASM) alternation, This method, called MBD-SNP, features affinity enrichment or methylated genomic DNA fragments using a methyl-binding domain polypeptide.


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Document History
  • Publication: Feb 5, 2019
  • Application: May 18, 2017
    US US 201715598684 A
  • Priority: May 18, 2017
    US US 201715598684 A
  • Priority: Jan 23, 2014
    US US 201414162180 A
  • Priority: Jan 23, 2013
    US US 201361755688 P

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