{"search_session":{},"preferences":{"l":"es","queryLanguage":"es"},"patentId":"014-139-246-075-235","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"014-139-246-075-235","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8838,"type":"PATENT","title":"Univ of Illinois Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":10245,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8209,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
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Search Applicants and Owners separately: uni* illinois chicago
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Search Applicants and Owners separately = \"Univ Illinois\", \"Illinois Univ\", \"University of Illinois\", \"Illinois University\", \"University Illinois NOT Northern NOT southern NOT State\".
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a) contacting the pancreatic tissue of the mammal that includes the pancreatic islets a solution that includes polymerized hemoglobin derived from mammalian blood and a proteolytic enzyme; wherein the solution includes a concentration of between 5 and 15 g/dL of polymerized hemoglobin; and thereafter\n
b) recovering the pancreatic islets from the mammalian tissue, thereby isolating the pancreatic islets."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the tissue is human pancreatic tissue and the polymerized hemoglobin is derived from human blood."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein the polymerized hemoglobin derived from human blood is pyridoxylated."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein the solution is oxygenated."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein the contacting step is achieved by intraductal administration."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, further including the step of washing the pancreatic islets with a cell culture medium to produce washed pancreatic islets."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 6, further including the step of purifying the washed pancreatic islets by density gradient centrifugation."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the solution further includes a cell culture medium."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 8, wherein the cell culture medium is RPMI."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the proteolytic enzyme is collagenase."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the solution further includes a buffer."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the polymerized hemoglobin is derived from human blood and is pyridoxylated."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 12, wherein the solution further includes a cell culture medium."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 13, wherein the proteolytic enzyme is collagenase and the cell culture medium is RPMI."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 14, wherein the solution is oxygenated."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the solution is oxygenated."],"number":16,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}