US 9714424 B1 - Rnai Inhibition Of Usp10 To Treat Ocular Disorders - The Lens

Rnai Inhibition Of Usp10 To Treat Ocular Disorders

Published: Jul 25, 2017
Earliest Priority: Dec 16 2014
Family: 1
Cited Works: 13
Cited by: 0
Cites: 2
Sequences: 19
Additional Info: Cited Works Full text Published Sequence

Data obtained from: USPTO Fulltext EMBL-EBI Pat NCBI GenBank DDBJ Pat

19 sequences found in this patent (in total)

Download sequences in fasta format: 7 RNAs 12 DNAs

Displaying 1 - 10 of 19 sequences

SEQ ID NO

Length

Sequence Type

Locations

Declared organism

Determined organism

Occurrence

Tools

SEQ ID NO

Length

3,520

Sequence Type

RNA

Locations

Detailed Description, Summary

Declared organism

Homo sapiens

Determined organism

Occurrence

Tools

SEQ ID NO

Length

Sequence Type

RNA

Locations

Claims, Detailed Description, Summary

Declared organism

Homo sapiens

Determined organism

Pan troglodytes
Pan troglodytes
Public DB hit
GI:332846498
XM_511147
1 of 2 hits reported for Pan troglodytes.

Hit length
3,410 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
XM_511147

0.56% cov

Alignment Length
19 bp

CIGAR string
19M mismatches: 0 - insertions: 0 - deletions: 0
Nomascus leucogenys
Nomascus leucogenys
Public DB hit
GI:332246807
XM_003272496
1 of 2 hits reported for Nomascus leucogenys.

Hit length
3,356 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
XM_003272496

0.57% cov

Alignment Length
19 bp

CIGAR string
19M mismatches: 0 - insertions: 0 - deletions: 0
Pongo abelii
Pongo abelii
Public DB hit
GI:297699362
XM_002826711
1 of 2 hits reported for Pongo abelii.

Hit length
3,478 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
XM_002826711

0.55% cov

Alignment Length
19 bp

CIGAR string
19M mismatches: 0 - insertions: 0 - deletions: 0
Macaca mulatta
Macaca mulatta
Public DB hit
GI:297288290
XR_013647
1 of 4 hits reported for Macaca mulatta.

Hit length
3,102 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
XR_013647

0.61% cov

Alignment Length
19 bp
Homo sapiens
Homo sapiens
Public DB hit
GI:119220604
NM_005153
1 of 11 hits reported for Homo sapiens.

Hit length
3,399 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
NM_005153

0.56% cov

Alignment Length
19 bp
Canis lupus familiaris
Canis lupus familiaris
Public DB hit
GI:73957165
XM_536761

Hit length
3,343 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
XM_536761

0.57% cov

Alignment Length
19 bp
synthetic construct
synthetic construct
Public DB hit
GI:168274447
AB383788
1 of 3 hits reported for synthetic construct.

Hit length
2,450 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 2

100% cov
AB383788

0.78% cov

Alignment Length
19 bp

Occurrence

14 times in PatSeqDB

in 2 extended families
(1 referenced in claims)
in 3 simple families
(1 referenced in claims)
in 14 documents

Tools

SEQ ID NO

Length

Sequence Type

RNA

Locations

Claims, Detailed Description, Summary

Declared organism

Homo sapiens

Determined organism

Occurrence

Tools

SEQ ID NO

Length

Sequence Type

RNA

Locations

Claims, Detailed Description, Summary

Declared organism

Homo sapiens

Determined organism

Pan troglodytes
Pan troglodytes
Public DB hit
GI:332846498
XM_511147
1 of 2 hits reported for Pan troglodytes.

Hit length
3,410 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 4

100% cov
XM_511147

0.56% cov

Alignment Length
19 bp

CIGAR string
19M mismatches: 0 - insertions: 0 - deletions: 0
Nomascus leucogenys
Nomascus leucogenys
Public DB hit
GI:332246807
XM_003272496
1 of 2 hits reported for Nomascus leucogenys.

Hit length
3,356 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 4

100% cov
XM_003272496

0.57% cov

Alignment Length
19 bp

CIGAR string
19M mismatches: 0 - insertions: 0 - deletions: 0
Pongo abelii
Pongo abelii
Public DB hit
GI:297699362
XM_002826711
1 of 2 hits reported for Pongo abelii.

Hit length
3,478 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 4

100% cov
XM_002826711

0.55% cov

Alignment Length
19 bp

CIGAR string
19M mismatches: 0 - insertions: 0 - deletions: 0
Macaca mulatta
Macaca mulatta
Public DB hit
GI:297288290
XR_013647
1 of 4 hits reported for Macaca mulatta.

Hit length
3,102 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 4

100% cov
XR_013647

0.61% cov

Alignment Length
19 bp
Homo sapiens
Homo sapiens
Public DB hit
GI:119220604
NM_005153
1 of 12 hits reported for Homo sapiens.

Hit length
3,399 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 4

100% cov
NM_005153

0.56% cov

Alignment Length
19 bp
synthetic construct
synthetic construct
Public DB hit
GI:168274447
AB383788
1 of 3 hits reported for synthetic construct.

Hit length
2,450 bp

E Value
2.65E-1

BLAST Score
38.2 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 4

100% cov
AB383788

0.78% cov

Alignment Length
19 bp

Occurrence

15 times in PatSeqDB

in 2 extended families
(2 referenced in claims)
in 3 simple families
(2 referenced in claims)
in 15 documents

Tools

SEQ ID NO

Length

Sequence Type

RNA

Locations

Claims, Detailed Description, Summary

Declared organism

Homo sapiens

Determined organism

Occurrence

Tools

SEQ ID NO

Length

Sequence Type

RNA

Locations

Claims, Detailed Description, Summary

Declared organism

Homo sapiens

Determined organism

Occurrence

10 times in PatSeqDB

in 2 families
(1 referenced in claims)
in 10 documents

Tools

SEQ ID NO

Length

Sequence Type

RNA

Locations

Claims, Detailed Description, Summary

Declared organism

Homo sapiens

Determined organism

Occurrence

Tools

SEQ ID NO

Length

Sequence Type

DNA

Locations

Undetermined

Declared organism

Homo sapiens

Determined organism

Occurrence

Tools

SEQ ID NO

Length

Sequence Type

DNA

Locations

Undetermined

Declared organism

Homo sapiens

Determined organism

Pan troglodytes
Pan troglodytes
Public DB hit
GI:332817753
XM_516706
1 of 2 hits reported for Pan troglodytes.

Hit length
4,507 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
XM_516706

0.44% cov

Alignment Length
20 bp

CIGAR string
20M mismatches: 0 - insertions: 0 - deletions: 0
Nomascus leucogenys
Nomascus leucogenys
Public DB hit
GI:332252959
XM_003275573
1 of 2 hits reported for Nomascus leucogenys.

Hit length
3,352 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
XM_003275573

0.6% cov

Alignment Length
20 bp

CIGAR string
20M mismatches: 0 - insertions: 0 - deletions: 0
Pongo abelii
Pongo abelii
Public DB hit
GI:297670163
XM_002813201
1 of 2 hits reported for Pongo abelii.

Hit length
3,961 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
XM_002813201

0.5% cov

Alignment Length
20 bp

CIGAR string
20M mismatches: 0 - insertions: 0 - deletions: 0
Macaca mulatta
Macaca mulatta
Public DB hit
GI:297285168
XM_001113909
1 of 2 hits reported for Macaca mulatta.

Hit length
3,587 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
XM_001113909

0.56% cov

Alignment Length
20 bp
Rattus norvegicus
Rattus norvegicus
Public DB hit
GI:158517932
NM_147139
1 of 2 hits reported for Rattus norvegicus.

Hit length
3,696 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
NM_147139

0.54% cov

Alignment Length
20 bp
Homo sapiens
Homo sapiens
Public DB hit
GI:34147573
NM_002213
1 of 8 hits reported for Homo sapiens.

Hit length
3,392 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
NM_002213

0.59% cov

Alignment Length
20 bp
synthetic construct
synthetic construct
Public DB hit
GI:306921360
AB587397
1 of 6 hits reported for synthetic construct.

Hit length
2,414 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
AB587397

0.83% cov

Alignment Length
20 bp
Papio cynocephalus
Papio cynocephalus
Public DB hit
GI:176589
L12231

Hit length
2,427 bp

E Value
6.71E-2

BLAST Score
40.1 bits

Similarity

100%

Coverage

100%

Alignment (schematic)

SEQ ID NO 9

100% cov
L12231

0.82% cov

Alignment Length
20 bp

Occurrence

2 times in PatSeqDB

in 2 families
in 2 documents

Tools

SEQ ID NO

Length

Sequence Type

DNA

Locations

Undetermined

Declared organism

Homo sapiens

Determined organism

Occurrence

Tools

19 sequences found in this patent (in total)

Filter sequences

Displaying 1 - 10 of 19 sequences

Pan troglodytes

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

CIGAR string

Nomascus leucogenys

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

CIGAR string

Pongo abelii

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

CIGAR string

Macaca mulatta

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Homo sapiens

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Canis lupus familiaris

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

synthetic construct

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

Pan troglodytes

Public DB hit

Hit length

E Value

BLAST Score

Similarity

Coverage

Alignment (schematic)

Alignment Length

CIGAR string

Nomascus leucogenys