Methods And Compositions For Therapeutic Treatment

  • Published: Jul 10, 2008
  • Earliest Priority: Dec 28 2006
  • Family: 13
  • Cited Works: 1
  • Cited by: 2
  • Cites: 0
  • Additional Info: Full text
Abstract

Methods and compositions are described for the modulation of central nervous system and/or fetal effects of calcineurin inhibitors. Methods and compositions are described for the modulation of efflux transporter activity to increase the efflux of calcineurin inhibitors out of a physiological compartment and into an external environment. In particular, the methods and compositions disclosed herein provide for the increase of efflux transporter activity at Blood-Tissue, blood-CSF and placental-maternal barriers to increase the efflux of calcineurin inhibitor from physiological compartments, including central nervous system and fetal compartments.


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Document History
  • Publication: Jul 10, 2008
  • Application: Dec 26, 2007
    WO US 2007/0088827 W
  • Priority: Jul 31, 2007
    US US 95319207 P
  • Priority: May 25, 2007
    US US 94037507 P
  • Priority: Dec 28, 2006
    US US 88230606 P

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