Abstract

The invention relates to a method of treating neuronal apoptosis in a mammal using nucleic acid encoding HSV-2 ICP10PK, or a polypeptide encoded thereby. The invention further relates to a method of treating neuronal apoptosis in a mammal using ICP10PK in combination with a nucleic acid encoding bcl-2, or the polypeptide encoded thereby. The invention also relates to the use of ICP10PK and ICP10PK in combination with bcl-2 to treat non-neuronal diseases characterized by apoptosis.


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Document History
  • Publication: Jan 27, 2009
  • Application: Jan 22, 2003
    US US 33360703 A
  • Priority: Jan 22, 2003
    US US 33360703 A
  • Priority: Jul 26, 2001
    US US 0123545 W
  • Priority: Jul 26, 2000
    US US 22135200 P

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