Methods For Selectively Modulating Survivin Apoptosis Pathways

Abstract

The present invention, based on the discovery of a new biological phenomena, provides methods and compositions for use in identifying agents that modulate the phosphorylation of survivin, the interaction between survivin and p34cdc2-cyclin B1 kinase complex, and the interaction between survivin and caspase-9. Related methods and compositions can be used to modulate survivin regulated apoptosis.


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Document History
  • Publication: Jun 30, 2009
  • Application: Nov 12, 2002
    US US 29160702 A
  • Priority: Nov 12, 2002
    US US 29160702 A
  • Priority: Feb 29, 2000
    US US 51551400 A

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