{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"008-129-763-611-730","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"008-129-763-611-730"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8837,"type":"PATENT","title":"University of Minnesota Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":8933,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8208,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicant and Owners respectively = \"Univ Minnesota\" , \" Minnesota Univ\", \" University of Minnesota\", \"Minnesota University\", \"Univ Minne*\" , \" Minne* Univ*.
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Total patents: 7910
Search Applicant and Owners respectively = \"Univ Minnesota\" , \" Minnesota Univ\", \" University of Minnesota\", \"Minnesota University\", \"Univ Minne*\" , \" Minne* Univ*.
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Total patents: 7910
delivering an antisense oligonucleotide to said tumor, wherein said antisense oligonucleotide has the sequence shown in SEQ ID NO:7."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said antisense oligonucleotide hybridizes to casein kinase 2 nucleic acid sequences and reduces the expression thereof."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said delivery is intratumorally, intravenously or topically."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said antisense oligonucleotide is an encapsulated antisense oligonucleotide."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said antisense oligonucleotide is a phosphorothioate antisense oligonucleotide."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said antisense oliognucleotide is a siRNA."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said casein kinase 2 is casein kinase 2α."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said casein kinase 2 is casein kinase 2α′."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1, wherein said solid tumor originates in a location selected from the group consisting of prostate, bladder, breast, liver, kidney, brain, head, and neck."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["A method of reducing the size of a solid tumor in an individual, comprising\n
delivering an antisense oligonucleotide to said tumor, wherein said antisense oligonucleotide hybridizes to casein kinase 2 nucleic acid sequences and reduces the expression thereof, wherein said antisense oligonucleotide has the sequence shown in SEQ ID NO:7,\n
wherein said reduction in expression of casein kinase 2 results in a reduction in size of said tumor."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising an antisense oligonucleotide and a pharmaceutically acceptable carrier, wherein said antisense oligonucleotide hybridizes to casein kinase 2 nucleic acid sequences and reduces the expression thereof, wherein said antisense oligonucleotide has the sequence shown in SEQ ID NO:7."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 11, wherein said composition is encapsulated."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["An antisense oligonucleotide of up to 50 nucleotides in length comprising a portion of at least 8 consecutive nucleotides of SEQ ID NO:7 , wherein said antisense oligonucleotide inhibits the expression of human casein kinase 2α."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["An antisense oligonucleotide of up to 50 nucleotides in length comprising a portion of at least 8 consecutive nucleotides of SEQ ID NO:7, wherein said antisense oligonucleotide inhibits the expression of human casein kinase 2α and 2α′."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 11, wherein said antisense oligonucleotide is a phosphodiester antisense oligonucleotide."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The antisense oligonucleotide of claim 13, wherein said antisense oligonucleotide is a phosphodiester antisense oligonucleotide."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The antisense oligonucleotide of claim 13, wherein said antisense oligonucleotide is encapsulated."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The antisense oligonucleotide of claim 13, further comprising a pharmaceutically acceptable carrier."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The antisense oligonucleotide of claim 14, wherein said antisense oligonucleotide is a phosphodiester antisense oligonucleotide."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The antisense oligonucleotide of claim 14, wherein said antisense oligonucleotide is encapsulated."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The antisense oligonucleotide of claim 14, further comprising a pharmaceutically acceptable carrier."],"number":21,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}