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Search Applicants and Owners separately: Dartmouth colle*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2346
Search Applicants and Owners separately: Dartmouth colle*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2346
A dynamic mechanical analyzer comprising an actuator and a force measuring device, the actuator adapted to apply a displacement in a first axis to a material over a range of frequencies, and the force measuring device adapted to monitor a mechanical response of the material;\n
A processor coupled to drive the actuator and to read the mechanical response, the processor coupled to execute machine-readable instructions of a poroelastic material model recorded in a memory;\n
The memory also containing limits;\n
The memory containing machine-readable instructions of a convergence procedure for determining parameters for the poroelastic model such that the model estimates the material response to within the limits."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The system of claim 1 further comprising a magnetic resonance elastography (MRE) system, and wherein the determined parameters are used to validate material property values acquired by the MRE system."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The system of claim 1 wherein the dynamic mechanical analyzer is configured to measure the response of the porous material over a plurality of frequencies, and wherein the machine-readable instructions of the convergence procedure use the response over that plurality of frequencies to determine the model parameters."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The system of claim 1 wherein the determined parameters are provided to a computerized model of displacement of tumor tissue during neurosurgery."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["A system for modeling mechanical responses of tissue, comprising the system of claim 1 and a second mechanical model of in-vivo tissue, the processor configured to execute the second mechanical model, and the second mechanical model configured with the determined parameters."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The system of claim 1 wherein the poroelastic model is derived from Biot's Theory of Consolidation."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The system of claim 3 wherein the plurality of frequencies lie within a range from one to thirty hertz."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The system of claim 1 further comprising a second actuator coupled to provide a displacement to the material in a second axis perpendicular to the first axis."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["A method for determining parameters of a computerized poroelastic model comprising:\n
Applying a displacement to a sample of a material with an actuator at a particular frequency selected from a plurality of frequencies;\n
Determining a mechanical response of tissue to the applied displacement;\n
Executing machine readable instructions of a poroelastic computer model of mechanical properties of tissue recorded in a memory, the memory also containing limits; and\n
Converging parameters for the poroelastic model such that the model predicts mechanical response of the tissue to within the limits."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 9, further comprising:\n
Configuring a second mechanical model of in-vivo tissue with the determined parameters, and\n
Executing the second mechanical model with an observed displacement to determine tumor shift during surgery."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 10 further comprising using a non-slip platen between the sample and the actuator to prevent slip, and the computer model incorporating a non-slip boundary condition to better estimate hydraulic conductivity."],"number":11,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}