Radio-labelled Cross-linking Reagents

Abstract

A crosslinking reagent consisting of a first functional group capable of forming a covalent derivative with a material of interest; a second functional group capable of forming an in situ bond to a neighboring material upon activation; a cleavable bond separating said first and second groups; and a radioactive marker to identify the neighboring material after cleavage of said bond, whereby in situ protein interactions can be studied.


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Document History
  • Publication: Dec 11, 1984
  • Application: Jan 12, 1982
    US US 33894682 A
  • Priority: Jan 12, 1982
    US US 33894682 A

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