Methods And Systems For Reducing Inflammation By Neuromodulation Of T-cell Activity


Described herein are devices, systems and method of treating inflammation, including methods of treating a T-cell mediated disease. In particular, described herein are methods of treating inflammation including the steps of stimulating a subject's inflammatory reflex to inhibit the immune response and administering a T-cell modifying agent to modify the activity of splenic T-cells. Also described herein are systems for treating inflammation including an inflammatory reflex stimulation module and a T-cell response modifying module. The T-cell response modifying module typically modifies the response of splenic T-cells to enhance or otherwise regulate the effect of stimulation of the inflammatory reflex.

Download PDF
Document Preview
Document History
  • Publication: Dec 15, 2015
  • Application: Mar 31, 2009
    US US 41567109 A
  • Priority: Mar 31, 2009
    US US 41567109 A
  • Priority: Mar 31, 2008
    US US 7260308 P

Download Citation

Sign in to the Lens