Pyrazoloquinazolinones As Inhibitors Of Poly(adp-ribose)polymerase (parp)

  • Published: Jul 31, 2008
  • Earliest Priority: Jan 24 2007
  • Family: 2
  • Cited Works: 1
  • Cited by: 18
  • Cites: 6
  • Additional Info: Full text
Abstract

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV- induced skin damage, and as chemo- and/or radiosensitizers for cancer treatment.


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Document History
  • Publication: Jul 31, 2008
  • Application: Jan 24, 2008
    WO GB 2008050049 W
  • Priority: Jan 24, 2007
    GB GB 0701273 A

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