{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"002-471-611-786-254","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"002-471-611-786-254"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11848,"type":"PATENT","title":"University of Leipzig Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11627,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8460,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
a transceiver comprising a body vibratable at ultrasonic frequencies and an extensive surface for beam emanation, said transceiver located within an indented window in a circumferential wall of a shaft of said catheter, said transceiver being sunken relative to said shaft wall such that it is seated between raised shaft portions proximally and distally to said transceiver, said transceiver configured to produce an unfocused power beam for thermal tissue damage, the unfocused power beam being produced by vibration over said body of the transceiver and emanating from said extensive surface when said extensive surface is positioned away from a wall of said small vessel at a distance sufficient to allow blood to flow over said extensive surface; and\n
a controller programmed to vibrate said body to produce said unfocused beam having energy to heat surrounding blood such that blood contacting said extensive surface is heated and its density is reduced, causing it to be displaced by cooler blood which cools said extensive surface by convective cooling to a temperature of 50 degrees Celsius or less."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said body of said transceiver is mounted on a PCB, wherein trenches are constructed in the PCB for blood flow to enhance said cooling."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 2, comprising a gas-filled gap between said body and said PCB."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 3, wherein said gas-filled gap is unsealed and wherein surface tension retains air within said gap when said device is immersed in blood."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 4, further comprising conductive connections to the PCB across the gas-filled gap, wherein said conductive connections provide thermal linkage between said body and said PCB, thereby enabling the PCB to act as an additional heat dissipation surface for said device."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, further comprising a pump unit for actively pumping said blood around said transceiver."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said transceiver comprises a piezoelectric element and wherein said vibratable body is a body of said piezoelectric element."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said transceiver is thermally connected to a heat sink that is located within said circumferential wall of the catheter or in the blood flow; and wherein saline is pumped down the catheter to provide additional fluid flow around the transceiver and/or around the heat sink."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, further comprising a temperature sensor located in association with said transceiver."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 9, wherein said temperature sensor is located downstream of said transceiver in a flow direction of blood in a vessel within which said device is placed, thereby to measure temperature of blood that has passed said extensive surface."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 9, wherein said controller is configured for providing said power beam in a duty cycle, said controller being configured to modify said duty cycle and/or applied power in response to changes in temperature indicated by said temperature sensor."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 11, wherein said controller is configured to modify said duty cycle to control said surface to remain within a range of 40° C. to 50° C."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 9, controllable to stop said power beam when a temperature sensed by said sensor reaches or exceeds a predetermined safety threshold."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, located at the end of a catheter, and further comprising a temperature sensor located in association with said transceiver, wherein saline is pumped down the catheter to provide additional fluid flow around the transceiver and wherein a rate of pumping is controlled according to changes in temperature sensed by said temperature sensor."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 14, wherein said controller is configured to modify said rate of pumping to control said surface to remain within a range of 40° C. to 50° C."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said power beam is provided at a frequency of at least 8 Megahertz, and said vibratable body has a thickness not exceeding 0.3 millimeters, thereby to increase heat transfer from said body."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1 further comprising a distancing mechanism for positioning said transceiver at least said distance away from said vessel wall."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 17, wherein said distancing mechanism comprises a distancing device positioned on said catheter and extending radially away from said transceiver."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 18, wherein said distancing device is shaped in the form of a spring or a net."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, further comprising one member of the group consisting of: a controllable valve openable into a body lumen for controlling blood flow about said device, a Tec cooler device, metal channels in a PCB, and a distancing device for distancing said transceiver from a vessel wall."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 20, wherein said body of said transceiver has a thickness below 0.3 millimeters, thereby to increase heat transfer from said vibratable body."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, further comprising one member of the group consisting of: a heat sink thermally coupled to said body for dissipating heat from said device, a thermo-electric cooler device thermally coupled to said body for cooling said body, a printed circuit board wherein the body is mounted on the printed circuit board, and the printed circuit board has channels therein for allowing blood flow to cool said body, a pump for pumping blood around said device to cool said device, and a flow directing structure for directing said flow present in the vessel over the vibratable body in order to cool said device."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 22, wherein said heatsink comprises braiding along a wall of a catheter to which said device is attached."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 22, attached to a catheter and wherein said pump is located within said catheter."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 22, wherein said flow-directing structure comprises a balloon."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 22, wherein said flow directing structure comprises a shaft and a bending zone on the shaft, the bending zone directing said flow."],"number":26,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said displacement of heated blood by cooler blood sets up a chimney effect."],"number":27,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 27, whereby the extensive surface becomes subject to convective cooling when immersed in blood by said chimney effect set up by said unfocused beam."],"number":28,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said extensive surface is flat."],"number":29,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said catheter device comprises a flexible distal tip."],"number":30,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, wherein said catheter device comprises more than one ultrasonic transceiver."],"number":31,"annotation":false,"title":false,"claim":true},{"lines":["The device of claim 1, comprising a plurality of transceivers facing different directions, and wherein said controller is programmed to vibrate each of said transceivers to produce said unfocused beam having energy to heat surrounding blood such that blood contacting said extensive surface of each of said transceivers is heated and its density is reduced, causing it to be displaced by cooler blood which cools said extensive surface by convective cooling to a temperature of 50 degrees Celsius or less."],"number":32,"annotation":false,"title":false,"claim":true},{"lines":["An ultrasonic catheter device sized for insertion within a small vessel for producing ultrasonic beams, comprising:\n
a transceiver comprising a body vibratable at ultrasonic frequencies and an extensive surface for beam emanation, said transceiver located within an indented window in a circumferential wall of said catheter, said transceiver configured to produce an unfocused power beam for thermal tissue damage, the unfocused power beam being produced by vibration over said body of the transceiver and emanating from said extensive surface; said extensive surface positioned such that blood is allowed to flow over said extensive surface;\n
a controller programmed to vibrate said body to produce said unfocused beam having energy to heat surrounding blood such that blood contacting said extensive surface is heated and its density is reduced, causing it to be displaced by cooler blood which cools said extensive surface by convective cooling to a temperature of 50 degrees Celsius or less;\n"],"number":33,"annotation":false,"title":false,"claim":true},{"lines":["An ultrasonic catheter device sized for insertion within a small vessel for producing ultrasonic beams, comprising:\nwherein said body of said transceiver is mounted on a PCB and comprising a gas-filled gap between said body and said PCB; wherein trenches are constructed in the PCB for blood flow to enhance said cooling; wherein said gas-filled gap is unsealed and wherein surface tension retains air within said gap when said device is immersed in blood.\n
a transceiver comprising a body vibratable at ultrasonic frequencies and an extensive surface for beam emanation, said transceiver located within an indented window in a circumferential wall of said catheter, said transceiver configured to produce an unfocused power beam for thermal tissue damage, the unfocused power beam being produced by vibration over said body of the transceiver and emanating from said extensive surface; said extensive surface positioned such that blood is allowed to flow over said extensive surface;\n
a controller programmed to vibrate said body to produce said unfocused beam having energy to heat surrounding blood such that blood contacting said extensive surface is heated and its density is reduced, causing it to be displaced by cooler blood which cools said extensive surface by convective cooling to a temperature of 50 degrees Celsius or less;\n"],"number":34,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}wherein said body of said transceiver is mounted on a PCB and comprising a gas-filled gap between said body and said PCB; wherein trenches are constructed in the PCB for blood flow to enhance said cooling; wherein said gas-filled gap is unsealed and wherein surface tension retains air within said gap when said device is immersed in blood; and\nwherein said device further comprises conductive connections to the PCB across the gas-filled gap, wherein said conductive connections provide thermal linkage between said body and said PCB, thereby enabling the PCB to act as an additional heat dissipation surface for said device.\n