{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"199-160-171-512-853","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"199-160-171-512-853","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11811,"type":"PATENT","title":"TU Dresden Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":4969,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8441,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: tech* uni* dresden. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4718
Search Applicants and Owners separately: tech* uni* dresden. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4718
a.) providing a vector as defined in one of the claims 1 to 10,
b.) introducing said vector into somatic stem cells and/or progenitor cells by transfection or transduction,
c.) overexpression of the cyclin-dependent kinase and the cyclin in the cells transfected or transduced in step b., resulting in proliferation of the cells transfected or transduced in step b.or
a') exposing somatic stem cells and/or progenitor cells to a composition or compound as defined in one of the claims 1 to 4 resulting in proliferation of the cells."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["Method according to claim 14 using a vector as defined in claim 7 to 9 with the additional step of inducing the knockout of the cyclin-dependent kinase and the cyclin genes inserted into the somatic stem cells and/or progenitor cells after Step b., preferably by induction of a DNA recombinase activity, to stop the induced proliferation of the transfected or transduced cells and to start differentiation of the stem cells and/or progenitor cells."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["Vector as defined in one of the claims 1 to 10 or composition or compound as defined in one of the claims 1 to 4 for use in the expansion of neural stem cells and/or progenitor cells for the treatment of a human or an animal having a disease, disorder or condition of the central nervous system, preferably selected from the group consisting of a neurodegenerative diseases, developmental disorders of the central nervous system (CNS), or injury of the CNS caused by accidents or tumors, in particular Huntington's disease, Alzheimer's disease, Parkinson's disease, brain injury or trauma, spinal cord injury or trauma, stroke, multiple sclerosis, cancer, CNS lysosomal storage diseases and head trauma and epilepsy."],"number":16,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}