{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"161-693-032-894-92X","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"161-693-032-894-92X"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8906,"type":"PATENT","title":"Univ Pennsylvania Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":24238,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8221,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search applicants and owners= \"Univ Pennsylvania\", \"Pennsylvania Univ\", \"Univ Penns*\", \"Penn* Univ\", \"University of Pennsylvania\", \"Pennsylvania University\".
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Search applicants and owners= \"Univ Pennsylvania\", \"Pennsylvania Univ\", \"Univ Penns*\", \"Penn* Univ\", \"University of Pennsylvania\", \"Pennsylvania University\".
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i) contacting a) isolated HIV Vpr and b) isolated AIF in the presence of c) a test compound and\n
ii) comparing the level of isolated HIV Vpr binding to isolated AIF to the level of isolated HIV Vpr binding to isolated AIF in the absence of said test compound."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 further comprising a positive control assay that comprises the steps of:\n
i) contacting a) isolated HIV Vpr and b) isolated AIF in the presence of c) anti-Vpr antibodies which competitively bind to Vpr with respect to AIF and/or anti-AIF antibodies which competitively bind to AIF with respect to Vpr."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 wherein the concentration of test compound is between 1 μM and 500 μM."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 wherein the concentration of test compound is between 10 μM and 100 μM."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 1 wherein a series of test assays are performed using a series of dilutions of test compounds."],"number":5,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}