{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"141-351-243-276-384","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"141-351-243-276-384"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10791,"type":"PATENT","title":"The Hebrew University of Jerusalem - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":7593,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8259,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: \"hebrew univ* jerusalem\"; \"hebrew univ* jerus*\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1457
Search Applicants and Owners separately: \"hebrew univ* jerusalem\"; \"hebrew univ* jerus*\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1457
(a) a cell sample holder for holding a cell of said cells; and\n
(b) a first cell analyzer including:\n
(i) a magnetic field source for applying a magnetic field to said cell; and\n
(ii) a sensor for qualifying and/or quantifying an effect of said magnetic field on said cell."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, further comprising a second cell analyzer for qualifying and/or quantifying a feature of said cell."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 2, wherein said second cell analyzer is capable of detecting a morphological feature of said cell, a biochemical feature of said cell, a molecular feature of said cell, an electrical feature of said cell, a flow dynamics feature of said cell, a density of said cell, a membrane permeability feature of said cell and an optical feature of said cell."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, further comprising a cell manipulating device."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 4, wherein said cell manipulating device is selected from the group consisting of an electroporation chamber, an electroporation actuator, an ultrasound actuator, a laser actuator, a radiofrequency actuator, a microwave actuator, a mechanical actuator and a thermal actuator."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 4, wherein said cell manipulating device is capable of facilitating the introduction or removal of molecules from the cells or/and facilitating preservation of said cell or is capable of destroying said cell."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, wherein said magnetic field is an electromagnetic field."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, wherein said magnetic field source and said sensor are electromagnetic coils."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, wherein said magnetic field source and said sensor are incorporated into a single electromagnetic coil."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, wherein said first cell analyzer is capable of producing a transient magnetic field."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, wherein said cell sample holder is a capillary tube."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 6, wherein an internal diameter of said capillary tube is selected so as to restrict passage therethrough to a single cell."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 6, wherein said magnetic field source and said sensor are each arranged around a circumference of said capillary tube."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, wherein said magnetic field source is capable of generating a pulsating magnetic field."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, wherein said magnetic field source is capable of generating a magnetic field of alternating polarity."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 15, wherein said magnetic field source is capable of varying a polarity shift of said magnetic field of alternating polarity."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, further comprising a cell manipulator capable of manipulating said cell based on said effect of said magnetic field on said cell."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 1, further comprising a cell manipulator capable of introducing or removing molecules across the cell membrane."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The system of claim 18, wherein said cell preservation device is a cryopreserver."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["A method of identifying cells of interest in a cell sample comprising:\n
(a) labeling the cells of interest with at least one type of a magnetic or magnetizable moiety;\n
(b) exposing each cell of the cell sample to a magnetic field;\n
(c) measuring a response of each cell of the cell sample to said magnetic field; and\n
(d) identifying the cells of interest according to said response."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said response is current generated in a coil by a magnetic field of said magnetizable moiety."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, further comprising the step of analyzing at least one feature of at least a subset of cells of the cell sample prior to, during or following step (b)."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 22, wherein said at least one feature is selected from the group consisting of a morphological feature, a biochemical feature, a molecular feature, an electrical feature, a flow dynamics feature, a density feature, a membrane permeability feature and an optical feature."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, further comprising the step of manipulating cells of interest."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, further comprising the step of separating said cells of interest from the cell sample according to said response."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 24, wherein said manipulating includes subjecting the cells of interest to an electroporation field."],"number":26,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, further comprising the step of cryopreserving the cells of interest."],"number":27,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said subset of cells includes unlabeled cells."],"number":28,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said subset of cells includes the cells of interest."],"number":29,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said cells of interest are labeled with two types of magnetic or magnetizable moieties and whereas step (d) includes identifying of cells labeled with one type of said two types of magnetic or magnetizable moieties or with said two types of magnetic or magnetizable moieties."],"number":30,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein step (d) is effected by measuring an effect of a magnetic field generated by said at least one magnetic or magnetizable moiety on an induction coil."],"number":31,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said magnetic field is a pulsating magnetic field source."],"number":32,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said magnetic field is of alternating polarity."],"number":33,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 33, wherein said magnetic field of alternating polarity is of varying polarity shift."],"number":34,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein the cell sample is a biological sample."],"number":35,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein the cells of interest are stem cells."],"number":36,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 36, wherein said stem cells are adult stem cells."],"number":37,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 37, wherein said adult stem cells are hematopoietic stem cells."],"number":38,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 37, wherein said adult stem cells are mesenchymal stem cells."],"number":39,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein the cells of interest are fetal cells."],"number":40,"annotation":false,"title":false,"claim":true},{"lines":["A cell preservation device comprising a cell chamber being configured for:\n
(a) permeabilizing a membrane of a cell;\n
(b) introducing a cell preserving composition into said cell."],"number":41,"annotation":false,"title":false,"claim":true},{"lines":["The cell preservation device of claim 41, wherein said cell chamber is further configured for removing said cell preserving composition from said cell."],"number":42,"annotation":false,"title":false,"claim":true},{"lines":["The cell preservation device of claim 41, wherein said cell chamber is configured capable of performing step (a) and optionally (b) on a single cell."],"number":43,"annotation":false,"title":false,"claim":true},{"lines":["The cell preservation device of claim 41, wherein (a) is reversible permeabilization."],"number":44,"annotation":false,"title":false,"claim":true},{"lines":["The cell preservation device of claim 41, wherein said cell chamber includes two chambers separated by a membrane having an opening sized for trapping said cell therein."],"number":45,"annotation":false,"title":false,"claim":true},{"lines":["The cell preservation device of claim 45, wherein the device further includes at least one pair of electrodes flanking said membrane and whereas said membrane is fabricated from an electrically insulative material."],"number":46,"annotation":false,"title":false,"claim":true},{"lines":["The cell preservation device of claim 46, wherein said electrically insulative material is silicon nitride."],"number":47,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}