{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"140-240-316-094-015","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"140-240-316-094-015","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10827,"type":"PATENT","title":"University of Arizona - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":8025,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8279,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: Univ* AND Arizona;
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4153
Search Applicants and Owners separately: Arizona AND State AND Univ*;
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2581
Search Applicants and Owners separately: Univ* AND Arizona;
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 4153
Search Applicants and Owners separately: Arizona AND State AND Univ*;
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2581
(a) providing a bone marrow derived stem cell;\n
(b) providing a genetically altered non-lymphocyte cell;\n
(c) fusing the bone marrow derived stem cell with the genetically altered cell, thereby creating a fused non-lymphocyte cell; and\n
(d) measuring an indicator of migration for said fused non-lymphocyte cell."],"number":18,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 18, wherein steps (a) and (b) comprise obtaining or culturing the fused non-lymphocyte cell from a previous fusion of the bone marrow derived stem cell with the genetically altered non-lymphocyte cell."],"number":19,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 18, wherein step (d) comprises an in vitro scratch assay."],"number":20,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 18, wherein step (d) occurs in vivo."],"number":21,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 18, wherein said cell of step (b) is of epithelial origin."],"number":22,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 18, wherein said cell of step (b) is from a carcinoma or carcinoma cell line."],"number":23,"annotation":false,"claim":true,"title":false},{"lines":["A method for screening an effect of a biological or chemical agent on non-lymphocyte tumor cell migration, comprising the steps of:\n
(a) providing a fused cell derived from a fusion of a bone marrow derived stem cell with a genetically altered non-lymphocyte cell;\n
(b) contacting said fused cell with a biological or chemical agent; and\n
(c) determining whether non-lymphocyte tumor cell migration is promoted, inhibited, or unchanged."],"number":24,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 24, wherein said biological or chemical agent is an antibody against ubiquitin."],"number":25,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 25, wherein said antibody comprises MEL-14."],"number":26,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 25, wherein said antibody is selected from the group consisting of antibodies 14372 and 10C2-2."],"number":27,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 24, wherein step (a) includes providing a genetically altered skin, breast, or prostate cell."],"number":28,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 24, wherein step (b) occurs in vivo."],"number":29,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 24, wherein step (a) includes providing a genetically altered cell from a carcinoma or a carcinoma cell line."],"number":30,"annotation":false,"claim":true,"title":false},{"lines":["A method for inhibiting non-lymphocyte tumor cell migration, comprising:\n
contacting a non-lymphocyte tumor cell with an effective amount of an antibody against ubiquitin."],"number":31,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 31, wherein said antibody comprises MEL-14."],"number":32,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 31, wherein said antibody is selected from the group consisting of antibodies 14372 and 10C2-2."],"number":33,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 31, wherein said contacting occurs in vitro."],"number":34,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 31, wherein said non-lymphocyte tumor cell is from a carcinoma or carcinoma cell line."],"number":35,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 35, wherein said carcinoma cell is human derived."],"number":36,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 35, wherein said carcinoma cell is selected from the group consisting of breast, prostate, and skin cells."],"number":37,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}