{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"127-910-897-393-695","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"127-910-897-393-695","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8892,"type":"PATENT","title":"University of Wisconsin Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":15082,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8214,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners = \"Wisconsin University\" , \"University of Wisconsin\", \"Wisconsin Univ\", \" Univ Wisconsin\" , \"Wisco* Alum* Res* Found*\".
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Search Applicants and Owners = \"Wisconsin University\" , \"University of Wisconsin\", \"Wisconsin Univ\", \" Univ Wisconsin\" , \"Wisco* Alum* Res* Found*\".
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determining the level of estrogen-related receptor (ERR) α expression in breast cancer cells of a breast cancer patient; and\n
comparing the ERRα level of the patient to a median ERRα level of a population of at least twenty-five breast cancer patients as expressed in their breast cancer cells wherein, on average, breast cancer patients with an ERRα level higher than the median level have a shorter survival time than breast cancer patients with an ERRα level lower than the median level."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["A method for categorizing breast cancer patients based on ERRα status comprising the steps of measuring the expression level of ERRα in the breast cancer cells of a breast cancer patient and determining whether the expression level is high or low by comparing the ERRα level of the patient to a median ERRα level of a population of at least twenty-five breast cancer patients as expressed in their breast cancer cells."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2 further comprising the step of identifying a breast cancer patient as unlikely to respond to hormonal blockade therapy if the breast cancer cells express ERRα at a high level."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2 further comprising the step of identifying a breast cancer patient as likely to respond to hormonal blockade therapy if the breast cancer cells express ERRα at a low level."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein the expression level of ERRα is determined by measuring ERRα mRNA."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2, wherein the expression level of ERRα is determined by measuring ERRα protein."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2 further comprising the step of determining the expression level of estrogen receptor (ER)α in the breast cancer cells of a breast cancer patient."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 7 further comprising the step of identifying a breast cancer patient as unlikely to respond to hormonal blockade therapy if the breast cancer cells express ERRα at a level higher than or similar to ERα ."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 7 further comprising the step of identifying a breast cancer patient as likely to respond to hormonal blockade therapy if the breast cancer cells express ERRα at a level lower than ERα ."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 7, wherein the expression level of at least one of ERRα and ERα is determined by measuring mRNA."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 7, wherein the expression level of at least one of ERRα and ERα is determined by measuring protein."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 2 further comprising the step of determining the expression level of ErbB2 in the breast cancer cells of a breast cancer patient."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 12 further comprising the step of identifying a breast cancer patient as likely to respond to ErbB2-based therapy if the breast cancer cells of the patient express ErbB2 at a high level and ERRα at a high level."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 12 further comprising the step of identifying a breast cancer patient as unlikely to respond to ErbB2-based therapy if the breast cancer cells of the patient express ErbB2 at a high level and ERRα at a low level."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 12, wherein the expression level of at least one of ERRα and ErbB2 is determined by measuring mRNA."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 12, wherein the expression level of at least one of ERRα and ErbB2 is determined by measuring protein."],"number":16,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}