{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"105-064-179-020-220","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"105-064-179-020-220","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8904,"type":"PATENT","title":"Univ Washington Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":15386,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8219,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search applicants and owners= \"Univ Washington', \"Washington Univ\", \"University of Washington\", \" Washington University\", \"Univ Washington NOT state\", \" Univ Washington NOT state NOT George\".
Select more for logical variants
Add to collection
Total patent: 10892
Search Applicants and Owners separately : \"wash* univ* st* lou*\"; \"univ* wash* lou*\"; \"Washington University St Louis\"; \"Wash* U* St Lo*\", \" Wash* U* in St Lo*\";
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 9644
Search applicants and owners= \"Univ Washington', \"Washington Univ\", \"University of Washington\", \" Washington University\", \"Univ Washington NOT state\", \" Univ Washington NOT state NOT George\".
Select more for logical variants
Add to collection
Total patent: 10892
Search Applicants and Owners separately : \"wash* univ* st* lou*\"; \"univ* wash* lou*\"; \"Washington University St Louis\"; \"Wash* U* St Lo*\", \" Wash* U* in St Lo*\";
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 9644
(i) forming a potassium channel having a unit conductance of 80-120 pS and having increased potassium channel current amplitude above intracellular pH of 7.1, when the monomer is expressed in Xenopus oocyte; and\n
(ii) encoded by a nucleic acid that specifically binds under stringent hybridization conditions to the complement of a nucleic acid encoding an amino acid sequence of SEQ ID NO:16 or SEQ ID NO:18, wherein the hybridization reaction is incubated at 42° C. in a buffer comprising 50% formamide, 5×SSC, and 1% SDS, and washed at 65° C. in a buffer comprising 0.2×SSC and 0.1% SDS."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["An isolated monomer of claim 1, wherein the monomer has an amino acid sequence of SEQ ID NO:16 or SEQ ID NO:18."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["An isolated monomer of claim 1, wherein the monomer has a molecular weight of about 126 kDa, which is calculated from amino acid sequence of the monomer."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["An isolated monomer of claim 1, wherein the monomer is a subunit of a homomeric potassium channel."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["An isolated polypeptide monomer of a pH sensitive potassium channel, the monomer:\n
(i) forming a potassium channel having a unit conductance of 80-120 pS and having increased potassium channel current amplitude above intracellular pH of 7.1, when the monomer is expressed in Xenopus oocyte; and\n
(ii) encoded by a nucleic aid that specifically binds under stringent hybridization conditions to the nucleic acid disclosed in SEQ ID NO:17 or SEQ ID NO:19, wherein the hybridization reaction is incubated at 42° C. in a buffer comprising 50% formamide, 5×SSC, and 1% SDS, and washed at 65° C. in a buffer comprising 0.2×SSC and 0.1% SDS."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["An isolated monomer of claim 5, wherein the monomer has an amino acid sequence of SEQ ID NO:16 or SEQ ID NO:18."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["An isolated monomer of claim 5, wherein the monomer has a molecular weight of about 126 kDa, which is calculated from amino acid sequence of the monomer."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["An isolated monomer of claim 5, wherein the monomer is a subunit of a homomeric potassium channel."],"number":8,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}