{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"103-467-927-206-869","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"103-467-927-206-869"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11671,"type":"PATENT","title":"University of Virginia - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":4846,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8334,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:uni* AND virginia
Select more for logical variants.
Add to collection.
Select all patents in the collection and expand by simple families.
Add to collection. Total patents: 4231
Search Applicants and Owners separately:uni* AND virginia
Select more for logical variants.
Add to collection.
Select all patents in the collection and expand by simple families.
Add to collection. Total patents: 4231
contacting a test leukocyte comprising at least one of said regulatory pathways with a test compound;\n
measuring the activity or function of at least one of said regulatory pathways,\n
wherein a lower level of said activity or function in the test leukocyte, compared with the level of activity or function in an otherwise identical leukocyte not contacted with said test compound, is an indication that said test compound inhibits leukocyte function."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 21, wherein said function is selected from the group consisting of adhesion, migration, arrest, activation of PAK, activation of PIX, PAK activity, PIX activity, induction of ROS formation, release of ROS, and cytoskeletal reorganization."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 21, wherein said regulatory pathway is PAK."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 23, wherein said method measures PAK phosphorylation."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said leukocyte is a neutrophil."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 20, wherein said method measures protein-protein interaction or complex formation."],"number":26,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}