{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"103-436-641-088-180","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"103-436-641-088-180","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11974,"type":"PATENT","title":"Thomas Jefferson University Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":2794,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8543,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:Jefferson Univ*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2672
Search Applicants and Owners separately:Jefferson Univ*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2672
R 1 is a linking moiety;
R 3 is SEQ ID NO: 1 IQLYQTF; SEQ ID NO:2 IHLYQTF; SEQ ID NO:3 CLQYLV; SEQ ID NO:4 CLEHLV; SEQ ID NO:5 CLQYLT; SEQ ID NO:6 CLEHLT; SEQ ID NO:7 CLQYLTQ; SEQ ID NO:8 CLEHLTQ; SEQ ID NO:9 PIAGSSQQ; SEQ ID NO:36 PICGSSQQ; SEQ ID NO:10 PLCGSAQH; SEQ ID NO:11 PLAGSAQH; SEQ ID NO:12 NHEPRFLS; SEQ ID NO:13 DYRHKFSL; SEQ ID NO:14 LNLQNL; SEQ ID NO:15 LKLQNL; SEQ ID NO:16 NLSESQL; or SEQ ID NO:17 KLSEQL; and
R 5 is a linking moiety."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The peptide of claim 3 wherein:
R 3 is SEQ ID NO:14 LNLQNL."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["A pharmaceutical composition comprising a peptide of claim 1 and a pharmaceutically acceptable carrier or diluent."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The pharmaceutical composition of claim 5 wherein said peptide is cyclic."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The pharmaceutical composition of claim 5 wherein said peptide is SEQ ID NO:31 CLNLQNLC."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["A pharmaceutical composition comprising a peptide and a pharmaceutically acceptable carrier or diluent, wherein said peptide mimics a loop on the γ-chain that interacts with either a cytokine or a γ-chain partner receptor chain of a heterodimeric cytokine receptor consists of 5-25 amino acids, inhibits signal transduction mediated by cytokine:receptor binding of cytokines that bind to receptors that comprise a γ-chain, is a conformationally restricted peptide having the formula: R 1 —R 3 —R 5 wherein:
R 1 is a linking moiety;
R 3 is SEQ ID NO:1 IQLYQTF; SEQ ID NO:2 IHLYQTF; SEQ ID NO:3 CLQYLV; SEQ ID NO:4 CLEHLV; SEQ ID NO:5 CLQYLT; SEQ ID NO:6 CLEHLT; SEQ ID NO:7 CLQYLTQ; SEQ ID NO:8 CLEHLTQ; SEQ ID NO:9 PIAGSSQQ; SEQ ID NO:36 PICGSSQQ; SEQ ID NO:10 PLCGSAQH; SEQ ID NO:11 PLAGSAQH; SEQ ID NO:12 NHEPRFLS; SEQ ID NO:13 DYRHKFSL; SEQ ID NO:14 LNLQNL; SEQ ID NO:15 LKLQNL; SEQ ID NO:16 NLSESQL; SEQ ID NO:17 KLSEQL; and
R 5 is a linking moiety."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The pharmaceutical composition of claim 8 wherein:
R 3 is SEQ ID NO:14 LNLQNL."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The peptide of claim 1 wherein said peptide is: SEQ ID NO: 31 CLNLQNLC. "],"number":10,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}