{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"086-061-764-261-075","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"086-061-764-261-075"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11848,"type":"PATENT","title":"University of Leipzig Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11627,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8460,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
a) detecting, in a nucleic acid sample from said human subject, at least one biomarker associated with the FTO gene; and
b) comparing the biomarker data obtained in step a) from said human subject to biomarker data from healthy and/or diseased people to make risk assessment and/or diagnosis and/or prognosis of obesity and/or type II diabetes in said human subject."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The method according to claim 1, wherein said at least one biomarker is selected from the group of single nucleotide polymorphisms (SNPs) listed in Table 2."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The method according to claim 1, wherein said at least one biomarker is a polymorphic site associated with at least one SNP selected from the group listed in Table 2."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The method according to claim 1, wherein said at least one biomarker is a polymorphic site being in complete linkage disequilibrium with at least one SNP selected from the group listed in Table 2."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for identifying human subjects at risk for developing obesity and/or type II diabetes."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for diagnosing obesity and/or type II diabetes in a human subject."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for selecting efficient and safe therapy to a human subject having obesity and/or type II diabetes."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for monitoring the effect of a therapy administered to a human subject having obesity and/or type II diabetes."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for predicting the effectiveness of a therapy to treat obesity and/or type II diabetes in a human subject in need of such treatment."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for selecting efficient and safe preventive therapy to a human subject at risk for developing obesity and/or type II diabetes."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for monitoring the effect of a preventive therapy administered to a human subject at risk for developing obesity and/or type II diabetes."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 4, wherein said method is for predicting the effectiveness of a therapy to prevent obesity and/or type II diabetes in a human subject at risk."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The method according to anyone of claims 1 to 12, wherein said at least one SNP listed in Table 2 is selected from rs9940128, rs1421085, rs1121980, rs17817449, rs3751812, rs11075990, and rs9941349."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["The method according to claim 13, wherein said at least one SNP listed in Table 2 is selected from rs9940128, rs1421085, rs1121980, and rs17817449."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The method according to claim 14, wherein said at least one SNP listed in Table 2 is rs1421085 or rs17817449."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["A test kit for using in an in vitro method according to anyone of claims 1 to 15, comprising appropriate means for:
a) assessing type and/or level of at least one biomarker associated with the FTO gene in a nucleic acid sample from a human subject; and
b) comparing the biomarker data assessed in a) from said human subject to biomarker data from healthy and/or diseased people to make risk assessment and/or diagnosis and/or prognosis of obesity and/or of type II diabetes in said human subject."],"number":16,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}