{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"082-956-317-266-474","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"082-956-317-266-474","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11855,"type":"PATENT","title":"University of Montpellier Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11808,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8467,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
R1 is selected from the group consisting of H, alkyl groups, and aralkyl groups, said alkyl or aralkyl groups being possibly substituted;\n
R2 is a group of formula NR3R4 or OR5, wherein R3 and R4 are independently selected from the group consisting of H, ORa, alkyl groups, aralkyl groups, and aryl groups, Ra being selected from the group consisting of H, alkyl groups, aryl groups, and aralkyl groups, wherein R3 and R4 may form, together with the nitrogen atom carrying them, a heterocyclyl group comprising from 5 to 20 atoms, possibly substituted, and R5 is selected from the group consisting of alkyl groups, aryl groups, and aralkyl groups, wherein R5 may form, together with the oxygen atom carrying it, a heterocyclyl group from 5 to 20 atoms, possibly substituted;\n
A is CH or N, or A is C and form, together with R1 and R2 and CO, a heterocyclyl group comprising from 5 to 20 atoms, possibly substituted;\n
X is CO, SO2, or CS;\n
R6 is H or an alkyl group, or may form together with R2 a heterocyclyl group from 20 to 30 atoms, or may form together with R1 a heterocyclyl group from 10 to 30 atoms; and\n
R7 is chosen from the group consisting of aryl groups and heteroaryl groups comprising 5 or 6 ring atoms, substituted by at least one NH2 group,\nor their pharmaceutically acceptable salts, hydrates or hydrated salts or its polymorphic crystalline structures, racemates, diastereomers or enantiomers, with the exclusion of the following compounds:"],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 13 having formula (I-ter):\n
wherein R1, R2, A, X and R6 are as defined in claim 13,\n
with the exclusion of the following compounds:"],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["A pharmaceutical composition comprising the compound according to claim 13, in association with a pharmaceutically acceptable vehicle."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["The pharmaceutical composition of claim 15, wherein said compound is the compound according to claim 14."],"number":16,"annotation":false,"claim":true,"title":false},{"lines":["A method of preventing viral pathologies or infections in a patient in need thereof, comprising the step of\n
administering to said patient a therapeutically effective amount of a compound of formula (I):\n\nwherein:\n
n is 0, 1 or 2;\n
A is CH or N, or A is C and form, together with R1, R2 and CO, a heterocyclyl group comprising from 5 to 20 atoms, possibly substituted;\n
X is CO, SO2 or CS,\n
R1 is chosen from the group consisting of: H, alkyl groups, and aralkyl groups, said alkyl or aralkyl groups being possibly substituted,\n
R2 is a group of formula NR3R4 or OR5, wherein:\n\nR3 and R4 being each independently chosen from: H, ORa, alkyl groups, aralkyl groups, and aryl groups, Ra being chosen from the group consisting of: H, alkyl groups, aryl groups, and aralkyl groups;\n\nwherein R3 and R4 may form, together with the nitrogen atom carrying them, a heterocyclyl group comprising from 5 to 20 atoms, possibly substituted,\nR5 is chosen from: alkyl groups, aryl groups, and aralkyl groups,\n\nwherein R5 may form, together with the oxygen atom carrying it, a heterocyclyl group from 5 to 20 atoms, possibly substituted,\n
R6 is H or an alkyl group, or may form together with R2 a heterocyclyl group from 20 to 30 atoms, or may form together with R1 a heterocyclyl group from 10 to 30 atoms,\n
R7 is chosen from the group consisting of: aryl groups, heteroaryl groups, —NHPh, heterocyclyl groups, and alkyl groups; wherein when R7 is aryl, heteroaryl or heterocyclyl, it is substituted by at least one NH2 group,\nwherein, when A is N, R1 and R2 may form, together with A and CO, a heterocyclyl group comprising from 5 to 20 atoms, possibly substituted,or its pharmaceutically acceptable salts, hydrates or hydrated salts or its polymorphic crystalline structures, racemates, diastereomers or enantiomers."],"number":17,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (II):\nwherein:\n
X, A, R1, R3 and R4 are as defined in claim 17, and\nR8 is chosen from the group consisting of: H, acyl groups, and heteroaryl groups."],"number":18,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (III):\nwherein R4 and Ra are as defined in claim 17."],"number":19,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (IV):\nwherein R3 and R4 are as defined in claim 17."],"number":20,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (V):\nwherein R1, R3 and R4 are as defined in claim 17."],"number":21,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (VI):\nwherein R3 and R4 are as defined in claim 17."],"number":22,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (VII):\nwherein R3 and R4 are as defined in claim 16, and R8 is a heteroaryl group."],"number":23,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (VIII):\nwherein R11 and R12 are, independently from each other, chosen from the group consisting of: H, alkyl, alkoxy, aryl, and aralkyl, and A′ is CH2 or NH."],"number":24,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (IX):\nwherein R3 and R4 are as defined in claim 17."],"number":25,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (X):\nwherein R3 and R4 are as defined in claim 17."],"number":26,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (XI):\nwherein R1, R3 and R4 are as defined in claim 17."],"number":27,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 17, wherein said compound has the following formula (XII):\nwherein:\n
X, A, R1, and R5 are as defined in claim 16, and\nR8 is chosen from the group consisting of: H, acyl groups, alkylcarbonyl groups, and heteroaryl groups."],"number":28,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}