{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"079-478-346-639-813","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"079-478-346-639-813","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11993,"type":"PATENT","title":"University of Connecticut Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3197,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8558,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:Univ* Connecti*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2880
Search Applicants and Owners separately:Univ* Connecti*. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2880
reacting an amine with a bromine-substituted oligo thiophene to form an amino-substituted oligo thiophene; and\n
reacting the amino-substituted oligo thiophene with a 4-methyl-N-alkyl-pyridinium salt to form the amino oligo thiophene dye;\n
wherein the amine has the structure HN(R1)(R2), wherein R1 and R2 are each independently hydrogen or optionally substituted C1-C10 alkyl, C3-C7 cycloalkyl, or phenyl;\n
wherein the bromine-substituted oligo thiophene has the structure\n\nwherein m is 1, 2, 3, or 4; n is 2, 3, 4, 5, or 6; each occurrence of R8, R9, R10, and R11 is independently hydrogen or halogen, or R10 and R11 collectively form ethylenedioxy (—OCH2CH2O—), provided that at least two adjacent thiophene groups can, optionally, be linked via a fused ring to form a dithiophene unit having the structure\nwherein R12 and R13 are each independently hydrogen or optionally substituted C1-C6 alkyl;\n
wherein the amino-substituted oligo thiophene has the structure\n\n
wherein R1, R2, R8, R9, R10, R11, m, and n are as defined above; and\n
wherein the 4-methyl-N-alkyl-pyridinium salt has the structure\n\nwherein R3 is optionally substituted C1-C10 alkyl; R4, R5, R6, and R7 are each independently hydrogen or fluorine; or R4 and R5 collectively form a fused aromatic ring, and/or R6 and R7 collectively form a fused aromatic ring; Xq−is an anionic counterion wherein q is 1 or 2 or 3; and p is 0, 1, 2, 3, or 4; and wherein the amino oligo thiophene dye has the structure\nwherein R1-R11, X, m, n, p, and q are as defined above."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["A biosensor comprising an amino oligo thiophene dye of claim 1 and, optionally, further comprising a conjugate of a protein and an amino oligo thiophene dye of claim 1; wherein the protein of the conjugate is covalently linked to the amino oligo thiophene dye."],"number":16,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}