{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"072-227-245-518-130","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"072-227-245-518-130","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10731,"type":"PATENT","title":"The University of North Carolina at Chapel Hill - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":8887,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8232,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:\"uni* north caro*\". Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1000
Search Applicants and Owners separately:\"uni* north caro*\". Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1000
wherein:\n\nm and n are independently 2;\neach L9 and L10 is C1-C5 alkylene;\nX20 and X21 are N;\nX22 is halo; and\neach D15 and each D16 are hydroxyl;\n
and\n
wherein the disorder is selected from the group consisting of Alzheimer's disease, Huntington's disease, amyotrophic lateral sclerosis, Rett syndrome, Parkinson's disease, spinal cord injury, stroke, ischemia, brain injury, motor neuron disease, multiple sclerosis, HIV dementia, peripheral nerve injury, hearing loss, and obesity."],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the subject is a human subject."],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the compound is represented by the structure:\n
or a pharmaceutically acceptable salt thereof."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["A method of facilitating neuronal or other cell survival, comprising contacting a cell with a compound represented by Formula (VII):\n
or a pharmaceutically acceptable salt thereof,\n
wherein:\n"],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 4, wherein the compound is represented by the structure:\nm and n are independently 2;\neach L9 and L10 is C1-C5 alkylene;\nX20 and X21 are N;\nX22 is halo; and\neach D15 and each D16 are hydroxyl.\n
or a pharmaceutically acceptable salt thereof."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 4, wherein the contacting is done in vitro."],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the compound is formulated in a unit dosage form comprising said compound and a pharmaceutically acceptable carrier."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 4, wherein the compound is formulated in a unit dosage form comprising said compound and a pharmaceutically acceptable carrier."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1 or 4, wherein each L9 and each L10 are C1-C3 alkylene."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 8, wherein each L9 and each L10 are C2 alkylene."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 1, wherein the disorder is selected from the group consisting of Alzheimer's disease, Huntington's disease, Rett syndrome, stroke, multiple sclerosis, and Parkinson's disease."],"number":11,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}