{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"064-477-292-521-799","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"064-477-292-521-799"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":8837,"type":"PATENT","title":"University of Minnesota Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":8933,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8208,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicant and Owners respectively = \"Univ Minnesota\" , \" Minnesota Univ\", \" University of Minnesota\", \"Minnesota University\", \"Univ Minne*\" , \" Minne* Univ*.
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Total patents: 7910
Search Applicant and Owners respectively = \"Univ Minnesota\" , \" Minnesota Univ\", \" University of Minnesota\", \"Minnesota University\", \"Univ Minne*\" , \" Minne* Univ*.
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Total patents: 7910
\n\n—Si(OR)3 (I)\n\n
wherein:\n
each R is independently selected from (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, (C2-C20)alkynylcarbonyl, wherein each (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, and (C2-C20)alkynylcarbonyl, is optionally substituted with one or more hydroxy, (C1-C6)alkoxy, oxo, halo, or aryl."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 1 wherein the taxane is a paclitaxel or docetaxel."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["A compound of formula (Ia):\n
wherein R1 is a group of formula (I),\n\n\n\n—Si(OR)3 (I)\n\n
wherein:\n"],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["A compound of formula (Ib):\neach R is independently selected from (C1-C20)alkyl, (C2-C20)alkenyl, (C2-C20)alkynyl, (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, and (C2-C20)alkynylcarbonyl, wherein each (C1-C20)alkyl, (C2-C20)alkenyl, (C2-C20)alkynyl, (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, and (C2-C20)alkynylcarbonyl, is optionally substituted with one or more hydroxy, (C1-C6)alkoxy, oxo, halo, or aryl;\nor a salt thereof.\n
wherein R1 and R2 are each independently a group of formula (I),\n\n\n\n—Si(OR)3 (I)\n\n
wherein:\n"],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["A compound of formula (Ic):\neach R is independently selected from (C1-C20)alkyl, (C2-C20)alkenyl, (C2-C20)alkynyl, (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, and (C2-C20)alkynylcarbonyl, wherein each (C1-C20)alkyl, (C2-C20)alkenyl, (C2-C20)alkynyl, (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, and (C2-C20)alkynylcarbonyl, is optionally substituted with one or more hydroxy, (C1-C6)alkoxy, oxo, halo, or aryl;\nor a salt thereof.\n
wherein R3 is a group of formula (I),\n\n\n\n—Si(OR)3 (I)\n\n
wherein:\n"],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["A compound selected from:\n\n\n\neach R is independently selected from (C1-C20)alkyl, (C2-C20)alkenyl, (C2-C20)alkynyl, (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, and (C2-C20)alkynylcarbonyl, wherein each (C1-C20)alkyl, (C2-C20)alkenyl, (C2-C20)alkynyl, (C1-C20)alkanoyl, (C2-C20)alkenylcarbonyl, and (C2-C20)alkynylcarbonyl, is optionally substituted with one or more hydroxy, (C1-C6)alkoxy, oxo, halo, or aryl;\nor a salt thereof.\n
and salts thereof."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["A compound selected from:\n\n\n
and salts thereof."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 1 and a PEG-b-PLGA block co-polymer."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 1 and a pharmaceutically acceptable carrier."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 1 and a PEG-b-PLGA block co-polymer."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 1 and one or more targeting moieties."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal comprising administering to the animal a compound as described in claim 1."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat restenosis in an animal comprising administering to the animal a compound as described in claim 1."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal, comprising administering to the animal a nano-particle as described in claim 10."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 3 and a PEG-b-PLGA block co-polymer."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 3 and a pharmaceutically acceptable carrier."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 3 and a PEG-b-PLGA block co-polymer."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 3 and one or more targeting moieties."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal comprising administering to the animal a compound as described in claim 3."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat restenosis in an animal comprising administering to the animal a compound as described in claim 3."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal, comprising administering to the animal a nano-particle as described in claim 17."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 4 and a PEG-b-PLGA block co-polymer."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 4 and a pharmaceutically acceptable carrier."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 4 and a PEG-b-PLGA block co-polymer."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 4 and one or more targeting moieties."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal comprising administering to the animal a compound as described in claim 4."],"number":26,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat restenosis in an animal comprising administering to the animal a compound as described in claim 4."],"number":27,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal, comprising administering to the animal a nano-particle as described in claim 4."],"number":28,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 5 and a PEG-b-PLGA block co-polymer."],"number":29,"annotation":false,"title":false,"claim":true},{"lines":["A composition comprising a compound as described in claim 5 and a pharmaceutically acceptable carrier."],"number":30,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 5 and a PEG-b-PLGA block co-polymer."],"number":31,"annotation":false,"title":false,"claim":true},{"lines":["A nano-particle comprising a compound as described in claim 5 and one or more targeting moieties."],"number":32,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal comprising administering to the animal a compound as described in claim 5."],"number":33,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat restenosis in an animal comprising administering to the animal a compound as described in claim 5."],"number":34,"annotation":false,"title":false,"claim":true},{"lines":["A method to treat cancer in an animal, comprising administering to the animal a nano-particle as described in claim 31."],"number":35,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}