{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"049-770-231-883-269","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"049-770-231-883-269","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11848,"type":"PATENT","title":"University of Leipzig Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11627,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8460,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
Search Applicants and Owners separately:univ* AND Leipzig. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1306
or a salt or ester thereof, wherein:\n"],"number":1,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 1, wherein the compound is a compound of formula Ia:\none of Z1 and Z2 is CR3 the other is N;\nX2 and X4 are independently C(O) or CH2;\nX3 is CRaRb;\nY is unsubstituted or substituted C1-C6 alkyl linker or a bond;\nm is 0, 1, 2, 3, 4;\nR1 is unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle, unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S, C(O)Rc or S(O)2Rc;\nR3 is H, halogen, unsubstituted or substituted C1-C8 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S;\neach R4 is independently hydroxyl, halogen, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C1-C6 alkoxyl, amino, unsubstituted or substituted C1-C6 alkylamino, unsubstituted or substituted di-(C1-C6) alkylamino, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle, unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S or any two adjacent R4's, together with the atoms to which they are attached, form a 5- to 7-member ring optionally comprising 1-4 heteroatoms selected from N, O and S;\nRa and Rb are independently H, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S; and\nRc is H, unsubstituted or substituted C1-C8 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S.\n
or a salt or ester thereof, wherein,\n"],"number":2,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 2, wherein X2 and X4 are each CH2, X3 is CRaRb wherein Ra and Rb are each H, and R3 is H."],"number":3,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 2, wherein m is 0, Y is unsubstituted or substituted C1-C6 alkyl linker and R1 is unsubstituted or substituted C5-C10 aryl."],"number":4,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 4, wherein R1 is unsubstituted or substituted phenyl."],"number":5,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 1, wherein the compound is a compound of formula Ib:\nX2 and X4 are independently C(O) or CH2;\nX3 is CRaRb;\nY is unsubstituted or substituted C1-C6 alkyl linker or a bond;\nm is 0, 1, 2, 3, 4;\nR1 is unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle, unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S, C(O)Rc or S(O)2Rc;\nR3 is H, halogen, unsubstituted or substituted C1-C8 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S;\neach R4 is independently hydroxyl, halogen, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C1-C6 alkoxyl, amino, unsubstituted or substituted C1-C6 alkylamino, unsubstituted or substituted di-(C1-C6) alkylamino, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle, unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S or any two adjacent R4's, together with the atoms to which they are attached, form a 5- to 7-member ring optionally comprising 1-4 heteroatoms selected from N, O and S;\nRa and Rb are independently H, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S; and\nRc is H, unsubstituted or substituted C1-C8 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S.\n
or a salt or ester thereof, wherein,\n"],"number":6,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 6, wherein X2 and X4 are each CH2, X3 is CRaRb, and Ra and Rb are each H."],"number":7,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 7, wherein m is 0, Y is unsubstituted or substituted C1-C6 alkyl linker and R1 is unsubstituted or substituted C5-C10 aryl."],"number":8,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 8, wherein R1 is unsubstituted or substituted phenyl."],"number":9,"annotation":false,"claim":true,"title":false},{"lines":["The compound of claim 1, wherein said compound is selected from the group consisting of:\n\n\n\nor a salt or ester thereof."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["A pharmaceutical composition comprising a compound of claim 1 and one or more pharmaceutically acceptable carriers."],"number":11,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}X2 and X4 are independently C(O) or CH2;\nX3 is CRaRb;\nY is unsubstituted or substituted C1-C6 alkyl linker or a bond;\nm is 0, 1, 2, 3, 4;\nR1 is unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle, unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S, C(O)Rc or S(O)2Rc;\neach R4 is independently hydroxyl, halogen, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C1-C6 alkoxyl, amino, unsubstituted or substituted C1-C6 alkylamino, unsubstituted or substituted di-(C1-C6) alkylamino, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle, unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S or any two adjacent R4's, together with the atoms to which they are attached, form a 5- to 7-member ring optionally comprising 1-4 heteroatoms selected from N, O and S;\nRa and Rb are independently H, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S; and\nRc is H, unsubstituted or substituted C1-C8 alkyl, unsubstituted or substituted C5-C10 aryl, unsubstituted or substituted heteroaryl comprising 1-4 heteroatoms selected from N, O and S, unsubstituted or substituted C3-C10 carbocycle or unsubstituted or substituted heterocycle comprising 1-4 heteroatoms selected from N, O and S.\n