{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"031-240-726-116-051","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"031-240-726-116-051"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10803,"type":"PATENT","title":"University of Groningen - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":1470,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8268,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: \"Univ* Groningen\"
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Search Applicants and Owners separately: univ* AND bruxe*
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Search Applicants and Owners separately: \"Univ* Groningen\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 883
Search Applicants and Owners separately: univ* AND bruxe*
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Select all patents in the collection and expand by simple families. Add to collection. Total patents: 2688
an IpaD polypeptide or functional derivative thereof;\n
a polynucleotide or functional fragment thereof encoding an IpaD polypeptide; and/or\n
an anti-IpaD neutralizing antibody."],"number":1,"annotation":false,"title":false,"claim":true},{"lines":["A composition for the treatment and/or the prevention of a Shigella infection, comprising at least one of the following elements:\n
an IpaD polypeptide or functional derivative thereof;\n
a polynucleotide or functional fragment thereof encoding an IpaD polypeptide;\n
and/or an anti-IpaD neutralizing antibody."],"number":2,"annotation":false,"title":false,"claim":true},{"lines":["The composition according to claim 1, wherein said IpaD polypeptide has an amino acid sequence identical or substantially similar to SEQ ID NO:1."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The composition according to claim 1, wherein said polynucleotide has a nucleotide sequence identical or substantially similar to SEQ ID NO:2."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1 wherein the anti-IpaD neutralizing antibody is polyclonal."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, wherein the anti-IpaD neutralizing antibody is monoclonal."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The composition of claim 1, further comprising a polyosidic antigen."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["A method for blocking entry of at least one Shigella serotype into a permissive cell, comprising contacting the cell with:\n
an IpaD polypeptide or functional derivative thereof;\n
a polynucleotide or functional fragment thereof encoding an IpaD polypeptide; and/or an anti-IpaD neutralizing antibody."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["A method for the treatment and/or the prevention of a Shigella infection, comprising administering to a host an effective amount of:\n
an IpaD polypeptide or functional derivative thereof;\n
a polynucleotide or functional fragment thereof encoding an IpaD polypeptide; and/or\n
an anti-IpaD neutralizing antibody."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 8, wherein said IpaD polypeptide has an amino acid sequence identical or substantially similar to SEQ ID NO:1."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 8, wherein said polynucleotide has a nucleotide sequence identical or substantially similar to SEQ ID NO:2."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 8 wherein the anti-IpaD neutralizing antibody is polyclonal."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 8, wherein the anti-IpaD neutralizing antibody is monoclonal."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 8, further comprising a polyosidic antigen."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["A kit for blocking entry of at least one Shigella serotype into a permissive cell,\n
comprising:\n
an IpaD polypeptide or functional derivative thereof;\n
a polynucleotide or functional fragment thereof encoding an IpaD polypeptide; and/or\n
an anti-IpaD neutralizing antibody."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["(canceled)"],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["A method as claimed in claim 8 for blocking entry of at least one Shigella serotype into a permissive cell, comprising the step of allowing the formation of an immune complex by contacting an anti-IpaD neutralizing antibody with a Shigella strain capable of infecting said permissive cell, said immune complex preventing or substantially reducing entry of said Shigella strain in the permissive cell."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 17, consisting of an in vivo method."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 17, wherein the anti-IpaD neutralizing antibody is produced by a host comprising said permissive cell following administration to said host of an IpaD polypeptide or functional derivative thereof and/or of a polynucleotide or functional fragment thereof encoding an IpaD polypeptide."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The method according to claim 19, wherein said IpaD polypeptide has an amino acid sequence identical or substantially similar to SEQ 10 NO:1."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The method according to claim 19, wherein said polynucleotide has a nucleotide sequence identical or substantially similar to SEQ 10 NO:2."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["The method of claim 17, wherein the anti-IpaD neutralizing antibody is provided to a host comprising said permissive cell by passively immunizing said host."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 9, wherein said IpaD polypeptide has an amino acid sequence identical or substantially similar to SEQ ID NO:1."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 9, wherein said polynucleotide has a nucleotide sequence identical or substantially similar to SEQ ID NO:2."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 9, wherein the anti-IpaD neutralizing antibody is polyclonal."],"number":25,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 9, wherein the anti-IpaD neutralizing antibody is monoclonal."],"number":26,"annotation":false,"title":false,"claim":true},{"lines":["A method according to claim 9, further comprising a polyosidic antigen."],"number":27,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}