{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"029-535-109-529-762","frontPageModel":{"patentViewModel":{"ref":{"entityRefId":"029-535-109-529-762","entityRefType":"PATENT"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":10798,"type":"PATENT","title":"Ghent University - Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":3552,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8263,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately: \"Ghent Univ*\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents:107
Search Applicants and Owners separately: \"Ghent Univ*\"
Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents:107
obtaining a Salmonella vaccine strain;\n
introducing a genetic modification within the cbpA gene or the scs locus of said vaccine strain; thereby obtaining said Salmonella mutant vaccine strain."],"number":10,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 10 where the genetic modification in the scs locus is located within the scsA, scsB, scsC, or scsD gene."],"number":11,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 10 wherein the genetic modification is a deletion of at least a portion of the cbpA gene or the scs locus."],"number":12,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 10 wherein the Salmonella vaccine strain consists of Salmonella enterica strain."],"number":13,"annotation":false,"claim":true,"title":false},{"lines":["The method of claim 13 wherein the Salmonella enterica strain consists of Salmonella enterica subspecies enterica serovar Typhimurium (Salmonella Typhimurium)."],"number":14,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 10, wherein the Salmonella vaccine strain is an attenuated strain."],"number":15,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 10, further comprising:\n
creating a PCR adjusted antibiotic resistance cassette,\n
inserting a first helper plasmid into the Salmonella vaccine strain,\n
substituting part or all of the cbpA gene or the scs locus with the PCR adjusted antibiotic resistance cassette,\n
controlling the substitution with PCR and sequencing,\n
inserting a second helper plasmid into the substituted target strain,\n
deleting the antibiotic resistance cassette and the helper plasmids, and\n
controlling the deletion with PCR and sequencing."],"number":16,"annotation":false,"claim":true,"title":false},{"lines":["A method for preventing, inhibiting or reducing recrudescence of a Salmonella infection comprising administering a Salmonella mutant vaccine strain as defined in claim 10 to a subject in need thereof."],"number":17,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 17, wherein the recrudescence is stress-induced."],"number":18,"annotation":false,"claim":true,"title":false},{"lines":["The method according to claim 17, wherein the subject is selected from the group consisting of a pig, poultry and cattle."],"number":19,"annotation":false,"claim":true,"title":false},{"lines":["A method for immunization of pigs, poultry and cattle against Salmonella infection comprising administering a Salmonella mutant strain vaccine as defined in claim 10 to a subject in need thereof."],"number":20,"annotation":false,"claim":true,"title":false},{"lines":["A method for administering an antigen heterologous to Salmonella to a subject for vaccination against an infectious agent comprising:\n
providing a Salmonella mutant strain according to claim 1;\n
introducing a heterologous nucleic molecule encoding the antigen into the Salmonella mutant strain; and\n
administering said Salmonella mutant strain to a subject in need thereof."],"number":21,"annotation":false,"claim":true,"title":false}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}